Institutional Review Board (IRB) Guide

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Navigating the IRB review process can be challenging. 
Below are some common questions and answers about IRB submission, review, and compliance:

What is the IRB?

The Institutional Review Board (IRB) works to protect the rights and welfare of human research subjects recruited to participate in research activities conducted within the institution with which it is affiliated. The mission of the NCWU IRB is to review, approve or deny research involving humans, with the intent to protect the rights and welfare of the research participants. 

How do I know if I am conducting research with human subjects?

How do I select and prepare the correct IRB application?

What are my responsibilities after IRB approval?

The principal investigator(s) and research team must conduct the study in accordance with the NCWU IRB-approved protocol. The following activities require further submission to the IRB:

  • Amendments:
    • Any modifications (change in recruitment, change in procedures or tests used, changes to data collection timeline, etc.) to the study must be approved by the IRB prior to implementation. Amendments should be sent to the Chair of the IRB.

  • Reportable Events:
    • Serious adverse events, unanticipated problems, protocol deviations and other events must be reported to the Chair of the IRB.

Frequently used IRB documents: